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Title Consumption of Yogurt, Low-Fat Milk, and Other Low-Fat Dairy Products Is Associated with Lower Risk of Metabolic Syndrome Incidence in an Elderly Mediterranean Population.
Authors Babio N, Becerra-Tomas N, Martinez-Gonzalez MA, Corella D, Estruch R, Ros E, Sayon-Orea C, Fito M, Serra-Majem L, Aros F, Lamuela-Raventos RM, Lapetra J, Gomez-Gracia E, Fiol M, Diaz-Lopez A, Sorli JV, Martinez JA, Salas-Salvado J
Source Journal of nutrition
Date of publication 2015
Volume 145
Issue 10
Pages 2308-16
Abstract BACKGROUND: The association between consumption of dairy products and the risk of developing metabolic syndrome (MetS) is unclear. OBJECTIVE: The purpose of this study was to evaluate the associations between consumption of dairy products (total and different subtypes) and incident MetS in a Mediterranean population at high cardiovascular disease risk. METHODS: We prospectively analyzed 1868 men and women (55-80 y old) without MetS at baseline, recruited from different PREDIMED (Prevencion con Dieta Mediterranea) centers between October 2003 and June 2009 and followed up until December 2010. MetS was defined according to updated, harmonized criteria. At baseline and yearly thereafter, we determined anthropometric variables, dietary habits by a 137-item validated food-frequency questionnaire, and blood biochemistry. Multivariable-adjusted HRs of MetS or its components were estimated for each of the 2 upper tertiles (vs. the lowest one) of mean consumption of dairy products during the follow-up. RESULTS: During a median follow-up of 3.2 y, we documented 930 incident MetS cases. In the multivariable-adjusted model, HRs (95% CIs) of MetS for the comparison of extreme tertiles of dairy product consumption were 0.72 (0.61, 0.86) for low-fat dairy, 0.73 (0.62, 0.86) for low-fat yogurt, 0.78 (0.66, 0.92) for whole-fat yogurt, and 0.80 (0.67, 0.95) for low-fat milk. The respective HR for cheese was 1.31 (1.10, 1.56). CONCLUSIONS: Higher consumption of low-fat dairy products, yogurt (total, low-fat, and whole-fat yogurt) and low-fat milk was associated with a reduced risk of MetS in individuals at high cardiovascular disease risk from a Mediterranean population. Conversely, higher consumption of cheese was related to a higher risk of MetS. This trial was registered at controlled-trials.com as ISRCTN35739639.
EMBASE keywords
Adverse effects // aged // animal // cheese // clinical trial // cohort analysis // controlled study // *dairy product // ethnology // feeding behavior // female // *geriatric nutrition // human // incidence // lipid diet // longitudinal study // *low fat diet // male // metabolic syndrome X/ep [Epidemiology] // metabolic syndrome X/et [Etiology] // metabolic syndrome X/pc [Prevention] // middle aged // *milk // multicenter study // prevalence // randomized controlled trial // risk factor // Spain // very elderly // *yoghurt/ae [Adverse Drug Reaction]
City of publication United States
Language eng
Accession Number PUBMED 26290009
EMBASE 26290009
DOI http://dx.doi.org/10.3945/jn.115.214593
Publication type Journal: Article
ID CN-01134588
Available Links PubMed